Differential expression of ASAH1 in cancer of the vulva.

Abstract

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of N-acylsphingosine amidohydrolase 1, encoded by ASAH1, in cancer of the vulva. ASAH1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).