The Use of Platelet-Rich Plasma Alone in The Treatment of Periodontal Endosseous Defects: A Report of Two Clinical Cases

Abstract

Background: On the basis of animal histologic data and randomized controlled trials, the authors provide \nreports of two cases, in which platelet-rich plasma (PRP) alone was used to treat periodontal endosseous \ndefects in patients exhibiting generalized severe chronic periodontitis. \nCase Descriptions: Clinicians treated endosseous defects with a probing pocket depth of 6 and 8 \nmillimeters (case 1), and 4 mm (case 2) by using PRP alone. At six months, complete periodontal pocket \nresolution, and significant clinical attachment gain and radiographic defect fill, compared with pre-surgical \nvalues, occurred in all defects. \nClinical Implications: PRP alone may be clinically and radiographically efficacious in the treatment of \nperiodontal endosseous defects.