Efficacy of Unani Formulation in Cervical Ectopy (Quruhal Rahim) - An Open Observational Study

Abstract

Introduction: Cervical ectopy (quruhal Rahim) is a benign and common gynaecological condition in India with 19% of the total population. About 80-85% of women suffer from Cervical Erosion. Cervical erosion is diagnosed by per speculum examination. Considering these facts methi, alsi,babuna, nakhuna, karamkalla, has been selected to evaluate the efficacy in the form of Abzan in Quruhal Rahim. Objective: To evaluate the efficacy of Abzan in Quruhal rahim with unani formulation. Methods: This is an open observational clinical study in clinically diagnosed woman (n=30) in the age group of 18-45 yrs having symptoms of vaginal discharge, normal or inflammatory changes in pap smear were included and patients with malignancy, Pelvic inflammatory disease, systemic illnesses & Sexually transmitted disease, oral contraceptive Pills and Intrauterine contraceptive device, pregnancy and lactation were excluded. Joshanda of methi 5gms, alsi 5gms, babuna 3gms, nakhuna 5gms, karmkalla 10 gms in 2 litres of warm water. After menses use daily one time for sitz bath for 15minuts for 21 days. The primary and secondary outcome was assessed. Cervical ectopy by arbitrary grading scale and SF-12 for Quality of life were health-related quality of the life is measured by SF-12 Questionnaire. To provide easily interpretable scales for physical and mental health. Results: Vaginal discharge mean score before and after treatment is 2.37±0.57 and0.367±0.49 respectively with p<0.0001. In cervical erosion, grading means score before and after treatment is 1.7±0.65 and 0.47±0.58 respectively with a p<0.0001. Highly significant improvement is found in subjective and objective parameters. Conclusion: This data suggests that the test drugs were safe, effective in improving and relieving symptoms of cervical erosion. Further, research in a larger sample size for longer duration is recommended.