Intraoperative Frozen Section Analysis - A Study of Tertiary Care Centre

Abstract

Intraoperative Frozen Section AnalysisA Study of the tertiary care centre Introduction: Frozen section (FS) is a key Histopathological technique used by pathologists during intraoperative consultation which will help operate surgeon to decide resection intraoperatively. FS is a rapid technique to evaluate tissue diagnosis, margins and lymph node metastasis. The present study aims to evaluate the accuracy, sensitivity and specificity of the frozen section with error rates of FS in our institute. Methods and Material: The present study was carried out at the Histopathology section of the department of Oncopathology at the tertiary care centre from 1st January 2018 to 31st December 2018. The data was obtained from our online Laboratory Information System (LIS). Fresh tissue was received in a clean sterile container. Gross examination and sectioning were done and the further procedure has been carried out in Cryostat. Rapid Haematoxylin and eosin staining were performed and slides were prepared. Statistical analysis was performed using Statistical Package for the Social Science Software (SPSS). Results: In the present study, the overall accuracy rate, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 94.93%, 98.96%, 91.17%, 92.13% and 98.96% respectively. The discordance rate was 5.07%. Conclusions: Frozen section is a reliable, accurate and rapid technique for intraoperative consultation which will help operate surgeons. Regular evaluation of discordance rate and analysis of methodology with technical skills will improve the accuracy rate of FS.