Archive | 2019
Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua
Abstract
The Bohadschia argus \xa0Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compounds\xa0group\xa0and to test\xa0the cytotoxic activity of ethanol extract of Bohadschia argus \xa0Jeager. The method for determining the group\xa0of chemical compounds was used the color reaction and precipitation\xa0using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), this\xa0method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compound\xa0group of\xa0\xa0 Bohadschia argus \xa0Jeager\xa0extract showed that the extract contained a lot of alkaloids\xa0secondary metabolites and few saponins. The results of\xa0testing of cytotoxic activity showed LC 50 \xa0value of 878.22 ppm. Base on\xa0the results of this study it can be concluded that the ethanol extract of Bohadschia argus \xa0Jeager\xa0has significant cytotoxic activity against Artemia salina \xa0Leach, so it can be considered as a chemotherapeutic agent.\xa0\xa0\xa0 Key words :\xa0Screening, chemical compounds,\xa0ethanol\xa0extract, B . argus ,\xa0BSLT.