Application of nanotechnology to counter antimicrobial resistance

Abstract

One of the main current health problems is the development of antimicrobial resistance. Currently, trials have been made to combat resistance developed by pathogens. These trials include thinking about non-traditional antimicrobial agents, development of novel antibiotics or formulations and modification of the traditional antimicrobial agents. Nanotechnology is increasingly utilized in many different clinical applications in our life, so it can present a potential answer to anti-microbial resistance, which could stimulate innovation and create a new generation of antimicrobial treatments. Because of nano size and unique physiochemical properties of nanoparticles, they can provide newer mechanisms of antimicrobial actions. This review article summarize mechanisms of action of antimicrobial agents and the different method of resistance developed by bacterial pathogens. After that we will examine in details using antimicrobial NPs and antibiotics delivery systems as new tools to tackle the current challenges in treating infectious diseases.