Economic viability in the use of agitated single-use bioreactors as an alternative to rigid systems in a prokaryotic plant

Abstract

Introduction: Nowadays, agitated single-use bioreactors are prominent in the pharmaceutical industry as potential alternatives to conventional rigid systems. This is due to the advantages associated with this technology. For example, it reduces operating costs due to the lack of cleaning and sterilization. However, in an economic evaluation, it is necessary to emphasize the associated costs of bags, the impact of disposal, the volumetric production capacity and the operational limits of the technology when compared with conventional systems.