Archive | 2021
Unique cesium-binding sites in proteins, a case study with the sacrificial sulfur transferase LarE
Abstract
Crystallography was used to characterize the cesium-binding sites in the sacrificial sulfur transferase LarE from Lactobacillus plantarum. Cs binding was unique when compared to a large range of other previously investigated metals. Database searches reveal that Cs preferentially binds to protein backbone carbonyl groups, often at crystal contacts and that the use of Cs in protein crystallography is an underutilized approach.