USE OF SLIDENAFIL CITRATE IN CASES OF INTRAUTERINE GROWTH RESTRICTION AT OBSTETRICS AND GYNAECOLOGY DEPARTMENT OF JLNMCH, BHAGALPUR, BIHAR

Abstract

Objective: Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation. Although, Sildena\uf001l citrate has shown promising results, there are no \uf001rm conclusion till now. The aim of our study is to evaluate the use of Sildena\uf001l citrate in the treatment of IUGR cases associated with impaired placental circulation. Materials And Methods: this was a prospective non-randomized study conducted at JLNMCH, Bhagalpur, Bihar starting from February 2019 to January 2020. The studied population included singleton pregnancy and suffering from IUGR associated with impaired placental circulation. Results: This study included 30 pregnant women. Cases were divided into two groups. The \uf001rst group received sildena\uf001l citrate and the second control group did not receive sildena\uf001l citrate. After 4 weeks after the 1st dose of Sildena\uf001l signi\uf001cant decrease in umbilical artery Doppler indices. There was a statistically signi\uf001cant difference in the mean birth weight at delivery and neonatal admission to the NICU in sildena\uf001l group. Conclusion: sildena\uf001le citrate treatment may present a new hope towards better perinatal outcomes for pregnancies complicated by IUGR and impaired placental circulation that may help to decrease neonatal admission to the NICU.