A RARE CASE OF MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN (MIS-C) TEMPORALLY RELATED TO COVID-19 IN A 2-MONTH-OLD INFANT WITH CARDIOVASCULAR AND NEUROLOGICAL INVOLVEMENT

Abstract

Multisystem In\uf002ammatory syndrome in Children (MIS-C) temporally associated to Coronavirus disease\n2019 (COVID-19) is a life-threatening condition. It has been commonly reported in the school going age\ngroup. We present a rare case of a two-month-old infant who was real time polymerase chain reaction (RT-PCR) positive for the\nsevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ful\uf001lling the World Health Organisation (WHO) criteria for MISC. Cardiac and in\uf002ammatory markers were raised at the time of admission with echocardiography showing biventricular\ndysfunction. Patient was treated with a course of intravenous immunoglobulin (IVIg) with rapid clinical improvement. During the\ncourse of hospital stay, patient developed generalised tonic-clonic seizures with magnetic resonance imaging (MRI) of the brain\nth suggestive of viral encephalitis. Patient was vitally stable and symptom free by the 10 day of admission and subsequ