A COMPARATIVE STUDY OF LEVELS OF HIGH SENSITIVITY CREACTIVE PROTEIN (hs-CRP) IN DIABETIC AND NON- DIABETIC POPULATION OF CENTRAL INDIA

Abstract

Background: Diabetes mellitus is the most common metabolic disorder characterized by metabolic abnormalities and\nlong term complications. It is characterized by hyperglycemia resulting from defect in insulin secretion and in its action. It\nhas become a leading cause of morbidity and mortality world over. hs- CRP is a marker of low-grade in\uf002ammation and it is raised in patients with\ntype 2 DM. The present study was undertaken with the objective of studying the relation of High Sensitivity CRP (hs-CRP) in patients of type 2\nDiabetes Mellitus and in non-diseased population. Methods: This was a comparative observational study, conducted at Diabetic clinic, Index\nMedical College, Indore during August 2014 to July 2015. Cases and control were selected as per the inclusion criteria. Statistical analysis was\ndone using SPSS v20. Mean age of the group was 48years. The mean hs CRP in the diabe Results: tic group was 0.45 compared with 0.35, in the\ncontrol group. hs CRP levels are directly related to insulin resistance and is Conclusion: highly associated with diabetic population.