Indian journal of applied research | 2021
A COMPARATIVE STUDY OF COMPLICATIONS OF MRM (MODIFIED RADICAL MASTECTOMY) VERSUS BCS (BREAST CONSERVATION THERAPY) IN EARLY INVASIVE BREAST CANCER. A RESULT FROM SAVERA CANCER AND MULTISPECIALITY HOSPITAL PATNA, BIHAR.
Abstract
Background: Early breast cancer patients admitted in the surgical oncology department of Savera Cancer and\nMultispeciality Hospital. Patients were divided in two treatment arms; Arm A and Arm B. Arm A patient went through\nMRM and Arm B patients went through BCS. This study included prospective cases of 1 year from June 2019 to June 2020.\nMethod: In all MRM group patients all breast tissue, skin, nipple areola complex and level 1, 2, 3 lymph nodes removed. In all BCS group\npatients lump was removed with an envelope of normal appearing breast tissue. In all resected specimens free surgical margin was ensured via\nhistopathology reports (HPR). Patients were reviewed in early post operative period for complications and follow up done at the end of 1st, 3rd,\n6th and 12th month for recurrence. In treatment Arm A (MRM) 08 patients developed arm ede Result: ma; 05 patients developed shoulder\ndysfunction; 07 patients developed \uf002ap necrosis; 07 patients developed arm dysesthesia. Whether in treatment ARM B (BCT) 04 patient had\nSeroma formation; 13 patients developed wound infection & wound contracture. Complications were reported in 35% of MRM group (35 out of\n100 cases), while they were absent in 65% (65 out of 100). However, in the BCS group, complications were reported in 6.66% cases only (15 out\nof 100 cases), while were absent in 93.33% (75 out of 100). P value by statistical analysis being 0.283, the difference being statistically\ninsigni\uf001cant. Recurrence were present in 6.66% of MRM group (8/100) while they were absent in 92.34 % (92/100). However in BCS group\nrecurrences were present in 3.33 % (3/100) and were absent in 97.67% (97/100). P value by statistical analysis being 1, the difference being\nstatistically insigni\uf001cant. Grading of complications has been captured from CTCAE Version 5.0 (Common Terminology Criteria for Adverse\nEvents).\nConclusion: There is slight signi\uf001cant difference in the recurrence rate, whether the patient had undergone BCS or MRM based on our short\nterm follow-up. However a long term follow-up is required.