TO COMPARE THE EFFECTS OF ROPIVACAINE(1.8mg/kg) WITH FENTANYL (50μg) AND ROPIVACAINE (1.8mg/kg) WITH CLONIDINE (75μg) FOR INTRAVENOUS REGIONAL ANAESTHESIA (IVRA) FOR UPPER LIMB AND LOWER LIMB SURGERIES

Abstract

Introduction: Intravenous Regional Anaesthesia (IVRA) is indicatedfor short surgical procedures of upper extremity(below elbow) and of lower\nextremity (below knee). The aim of this randomised double-blind controlled study was to investigate the effects of adding Injection Clonidine as\nadjuvant to Injection Ropivacaine and Injection Fentanyl as adjuvant to injection Ropivacaine for IVRA in patients undergoing upper limb (below\nelbow) and lower limb (below knee) surgeries. Sixty adult ASA I and II patients Material and methods: of either sex in the age range of 20 to 60\nyears were randomly divided equally into 2 groups of 30 each. Group A received Injection Ropivacaine(0.75%) 1.8 mg/kgwith Injection\nClonidine75µg/kg and Group B received Injection Ropivacaine (0.75%) 1.8 mg/kg with Injection Fentanyl 50 µg/kg. Results: Sensory onset\nshowed high statistically signi\uf001cant difference with Group A having earlier onset at 28.50 19.96 seconds as compared to Group B at 238 111.95\nseconds (P<0.0001). Comparison of peak sensory showed high signi\uf001cant statistical difference with Group A having earlier onset at 194 223.21\nseconds as compared to Group B at 720 217.19 seconds (P<0.0001). The sensory wearoff between both the groups were highly signi\uf001cant\nstatistically showing Group A at 1150 ± 486.19 seconds as compared with Group B 184 ± 112.45 seconds (P<0.0001). The Visual Analogue Score\nin post operative ward just after completion of surgery show Group B having higher VAS score as compared with Group A.The time for rescue\nanalgesia was prolonged in Group A as compared with Group B. Conclusion: Adding Clonidine to Ropivacaine improved the quality of\nanaesthesia and post-operative analgesia in Intravenous Regional Anaesthesia as compared to when Fentanyl was added to Ropivacaine.