Long Term Assessment for Delayed Toxicities of Radiotherapy for Cervical Cancer Patient with Systemic Lupus Erythematosus

Abstract

Using Radiation in patients with systemic lupus erythematosus (SLE), especially if discoid lesions are present within the radiation field, is associated with modest increase in the risk of acute and delayed toxicity. Thus, its use is relatively contraindicated. Here-in we describe a patient with active SLE and grade 4 renal dysfunction who presented with locally advanced cervical cancer Radiologically stage IIB (by CT and MRI), was treated with radiotherapy alone using intensity modulated radiotherapy (IMRT) in 2008. Patient did not experience any grade 3 or 4 acute toxicities which were reported before. Over the last ten years of follow up she did not experience any delayed toxicity, which supports the patient adapted radiotherapy with novel radiation therapy techniques.