Invasive Intestinal Aspergillosis in the Setting of Autologous Graft Versus Host Disease after Hematopoietic Cell Transplant for Multiple Myeloma

Abstract

Autologous stem-cell transplant is used to treat a variety of neoplastic syndromes such as multiple myeloma, chronic myeloid leukemia, and non-Hodgkin s lymphoma. In spite of its efficacy compared to other treatments, it predisposes patients to opportunistic infections and in rare cases, autologous graft versus host disease. In recent years, one opportunistic infection in particular, invasive aspergillosis, has become increasingly more common although survival rates remain low due to difficulty in diagnosis.