The Rationality of Using Diclofenac in Outpatient Cases of Osteoarthritis of RSUP MH Palembang Period January-March 2018

Abstract

Rationality of Diclofenac Use in Osteoarthritis Outpatient Case at RSUP MHPalembang in January-March 2018. Osteoarthritis (OA) is the most common diseasein joints that affects people in their middle until late years. In Indonesia the prevalenceof OA is relatively high and disturbs their daily activity. Diclofenac is one of the drug ofchoice in treating OA. To avoid multiple side effects from Diclofenac use, the usagemust be in accordance to rationality indicators which are correct dose, correctfrequency, and correct length of use. This study is aimed to know the rationality ofDiclofenac use in Osteoarthritis outpatient cases at RSUP Mohammad HoesinPalembang. This study is a descriptive observational with a cross-sectional approachto know the rationality of Diclofenac use in outpatient cases of osteoarthritis at RSUPMohammad Hoesin Palembang. Samples were medical records of OA patients inoutpatient setting from January to March 2018 which fulfilled the inclusion andexclusion criteria. Sampling technique used was total sampling. The amount ofsamples fulfilling the inclusion criteria were 201 patients, with the most were aged 46-65 years (60.2%), female (55.7%), and has a history of comorbidity which includes lowback pain (22.8%). The result of this study shows pattern of Diclofenac use with dosageof 2 x 25mg (73.6%), length of use about <7 days (57.2%). In combination with otherdrugs there were no interaction to be found (84.4%), or synergistic interaction (8.5%)and antagonistic interaction (7.1%). The use of diclofenac in osteoarthritis cases atoutpatient setting in RSUP Dr Mohammad Hoesin Palembang is rational and needs tobe maintained.