Microbial distribution of uropathogens in pediatric urinary stone patients in Kashgar Uyghur

Abstract

0bjective To investigate the characteristics of bacterial distribution associated with urinary tract infection in pediatric urinary stone patients in Kashgar Uyghur. \n \n \nMethods \nThe results of positive bladder urine culture from 479 pediatric patients with diagnosis of urinary calculi andurinary tract infection from January, 2012 and September, 2018 were retrospectively analyzed. There were 314 male and 165 female. The patients were stratified into three different age groups: A≤6 years, B 7-12years, C 13-18 years. The microbial distribution of uropathogens in the patients were analyzed on the basis of the results of the urine culture in different genders, ages, and years. \n \n \nResults \nThe four most common uropathogens were escherichia coli (282 strains; 58.87%), klebsiellapneumoniae (52 strains; 10.86%), enterococcus faecium (30 strains; 6.26%), and enterococcus faecalis (23 strains; 4.80%). The incidence of urinary infection was higher in the male than in the female [314 strains (65.55%) vs. 165 strains (34.45%); P 0.05). Other urinary tract bacteria except the top four pathogenic bacteria in 2016 were statistically different from those in 2014, 2015, 2017, and 2018 (P<0.05). \n \n \nConclusion \nThe microbial distribution of uropathogens in pediatric urinary stone patients is unique in gender and age. The proportion of total bacteria is higher in the male than in the female. The Urinary tract infection is commonly caused by escherichia coli. \n \n \nKey words: \nPediatric urolithiasis;\xa0Urinary tract infection;\xa0Uropathogens;\xa0Children