Archive | 2019
Effects of inhalation and intravenous anesthesia with sevoflurane versus total intravenous anesthesia on recovery of patients undergoing partial hepatic resection
Abstract
Objective \nTo investigate the effects of inhalation and intravenous anesthesia with sevoflurane versus total intravenous anesthesia on recovery of patients undergoing partial hepatic resection. \n \n \nMethods \nFifty ASA I or Ⅱ patients undergoing partial hepatic resection were allocated randomly into two group A and group B. After induction, general anesthesia was maintained with sevoflurane (0.3~0.5 MAC), propofol (1.5~3.0 μg/ml target plasma concentration) and remifentanil (2.0~8.0 ng/ml target plasma concentration) in group A and propofol (3.0~6.0 μg/ml target plasma concentration), remifentanil (2.0~8.0 ng/ml target plasma concentration) in group B. The times for respiration recovery, awakening, and extubation, as well as bucking response, were recorded. The Sedation-Agitation Scale and pain score were also noted 1 (T1), 5 (T2), 10 (T3), 20 (T4), 30 (T5), and 40 min (T6) after extubation. \n \n \nResults \nThe times for respiration recovery, awakening, and extubation in group A were shorter than those in group B [(8.0±3.5) mim vs. (15.0±5.2) min, (13.0±4.8) min vs. (20.6±6.0) min, and (14.7±5.1) mim vs. (22.4±7.1) min; all P<0.05]. The incidence of bucking response was higher in group A than in group B (60.0% vs. 20.0%, P<0.05). \n \n \nConclusion \nInhalation and intravenous anesthesia with sevoflurane can decrease the times of respiration recovery, extubating, and awakening; and total intravenous anesthesia can lower the incidence of bucking response in patients with partial hepatic resection. \n \n \nKey words: \nSevoflurane;\xa0Inhalation and intravenous anesthesia;\xa0Total intravenous anesthesia;\xa0Hepatic resection