The clinical treatment strategy for Bismuth-Corlette type III hilar cholangiocarcinoma

Abstract

Objective \nTo evaluate the result of peri-hilar resection(extrahepatic bile duct resection plus local hepatectomy) and hepaticojejunostomy for the treatment of Bismuth-Corlette type Ⅲ hilar cholangiocarcinoma (HCCA). \n \n \nMethods \nThis study was conducted on 37 patients divided into group A undergoing peri-hilar resection (extrahepatic bile duct resection combined with local hepatectomy) and hepaticojejunostomy (n=17) and group B treated by extrahepatic bile duct combined with hemihepatectomy and hemicaudatectomy and cholangioenterostomy (n=20). \n \n \nResults \nThe incidence of postoperative acute liver failure was lower in group A than in group B (χ2=5, 332, P=0.021). There was no significant difference in clinical data and survival rate (OS) between the two groups of patients and other complications. \n \n \nConclusion \nFor patients with Bismuth-Corlette type Ⅲ HCCA, the peri-hilar resection(extrahepatic bile duct combined with local hepatectomy)and hepaticojejunostomy reduces the incidence of postoperative acute liver failure. \n \n \nKey words: \nBile duct neoplasms;\xa0Hepatectomy;\xa0Anastomosis, surgical;\xa0Liver failure, acute