CTRP family in diabetes mellitus and its complications

Abstract

Complement-C1q/tumor necrosis factor-related protein (CTRP) family is a recently discovered adipokine, which is highly homologous with adiponectin. CTRP family plays an important role in the regulation of glycolipid metabolism, energy metabolism, inflammatory response and vascular protection. In recent years, the researchers found that CTRP family members can participate in the development of diabetes and its complications by regulating glucose metabolism, affecting insulin resistance, and is expected to provide new therapeutic targets for diabetes and its complications. \n \n \nKey words: \nComplement-C1q/tumor necrosis factor-related protein;\xa0Diabetes mellitus;\xa0Diabetic complications