Research progress of Fuchsu veitis

Abstract

Fuchs uveitis (FU) is a chronic, low-grade inflammatory disorder involving the uvea. Evidence accumulates that there is no doubt that rubella virus infection have been implicated in the pathogenesis of the disease. FU is also named Fuchs’ heterochromic iridocyclitis. But heterochromia is variable depending on amount of pigment in the iris pigmented epithelium and the intensity of the anterior iris atrophy. The diagnosis might often be delayed due to the absence of heterochromia. In addition, recent researches showed that FU might be an inflammatory condition involving the whole uveal tunic. Progression of the disease is associated with cataract formation and glaucoma. Recently, phacoemulsification combined with intracapsular intraocular lens implantation has been widely reported in the treatment of complicated cataract.Although the complications of angle hemorrhage and anterior chamber inflammation are higher than those of conventional cataract surgery, most of the patients have good postoperative visual acuity.Therapy for glaucoma associated to FU is often more challenging because of its poor response to drugs, lasers and surgical treatment than other types of glaucoma. If trabeculectomy is used, intraoperative use of antimetabolic drugs can increase the success rate of surgery. Some researchers have used new combined glaucoma and cataract surgery to treat the complications of the disease recently, and the long-term results need to be observed. (Int Rev Ophthalmol, 2019, 43: 62-67) \n \n \nKey words: \nFuchs’ uveitis;\xa0Fuchs’ syndrome;\xa0rubella virus