Risk factors of hypocalcemia and hypoparathyroidism after thyroidectomy

Abstract

Objective \nTo investigate the risk factors of hypocalcemia and hypoparathyroidism after thyroidectomy. \n \n \nMethods \nClinical data of 260 patients who underwent thyroidectomy in the Third People’s Hospital of Heze from September 2016 to October 2017 were retrospectively analyzed. Postoperative parathyroid hormone (PTH) and serum calcium concentration of the 260 patients were examined. Univariate analysis and multivariate analysis were used to screen the risk factors of postoperative hypothyroidism and hypocalcemia. \n \n \nResults \nAmong the 260 patients who underwent thyroidectomy in the study, 60 cases (23.08%) were complicated with hypoparathyroidism, and 47 cases (18.08%) were complicated with hypocalcemia. Univariate analysis showed that postoperative hypoparathyroidism was associated with cervical lymph node dissection, gender, surgical range, operation time, central region lymph node dissection and preoperative PTH level (P 1). According to univariate analysis, postoperative hypocalcemia was associated with cervical lymph node dissection, gender, operation range, operation time, central region lymph node dissection, and age (P 1). \n \n \nConclusions \nLarge operation range and high age are the main risk factors for postoperative hypocalcemia. The main risk factors for postoperative hypoparathyroidism are female, large surgical range and low preoperative PTH level. \n \n \nKey words: \nThyroidectomy;\xa0Hypoparathyroidism;\xa0Hypocalcemia;\xa0Risk factors