Zhonghua yi xue za zhi | 2021
[Pay more attention to the application of mesenchymal stem cells in the treatment for immune skin diseases].
Abstract
Mesenchymal stem cells (MSC) represents a heterogeneous group of multipotent non-hematopoietic stem cells with self-renewal and differentiating into mesenchymal cell lineage. Recent studies have demonstrated that MSC has low immunogenicity, which means it does not express major histocompatibility complex (MHC) class â…¡and other co-stimulating factors. Thus, due to the capability of anti-inflammatory and immunomodulatory effects, MSC therapy provides many possibilities for the treatment for immune skin diseases.