Progress in scar prevention and treatment

Abstract

At present, scar is one of the key areas of medical research, and its evaluation, prevention, and control methods have received more and more attention. Scar is generally divided into superficial scar, atrophic scar, hypertrophic scar, and keloid. The mechanism is thought to involve abnormal proliferation of fibroblasts and imbalance of secretion, synthesis, and degradation of collagen caused by various factors during the skin wound healing process, which eventually result in the formation of abnormal hypertrophic skin tissue. The severity of scar is measured mainly using the Vancouver scar scale (VSS), the Patient and Observer scar Assessment scale (POSAS) and so on. Its main treatments include pressure therapy, silicone gel therapy, radiation therapy, laser therapy, intralesional corticosteroids, and surgical therapy. Now it is believed that combination therapy is still the safe and effective strategy for the prevention and control of scar. \n \n \nKey words: \nScar;\xa0Hyperplastic;\xa0Keloid;\xa0Surgery;\xa0Combined therapy