Status and progress of new PET-CT probe application in gastric cancer

Abstract

Gastric cancer is a common malignant tumor in China, which has the characteristics of low survival rate and high morbidity, and its 10-year survival rate is about 15%. Therefore, it needs timely and accurate diagnosis and treatment. In recent decades, positron emission tomography (PET) using 18F-fluorine deoxidization glucose (18F-FDG) as a tracer has been proved to be available in a variety of malignant tumor diagnosis and evaluation to provide information about tumor metabolism. However, because of the physical uptake of gastric mucosa and voluntary exercise, some types of gastric malignant tumors may affect the detection ability of 18F-FDG in gastric cancer. Therefore, searching for more tumor-specific PET-CT imaging agents to make up for the deficiency of 18F-FDG is the focus of current nuclear medicine research. In this paper, the application status and prospect of this method in tracer of gastric cancer are reviewed. \n \n \nKey words: \nStomach neoplasms;\xa0Positron-emission tomography;\xa0Computed tomography;\xa0Radioactive tracers