Extracranial metastasis in a IDH- wild type glioblastoma

Abstract

Editor, Glioblastoma is the most common and most aggressive primary brain tumor. It usually spreads by direct extension and infiltration into the adjacent brain tissue and along with white matter tract rather than by metastasis. Extraneural metastasis from glioblastoma is rare despite the highly invasive nature with reported incidence of less than 2%. The rarity of this phenomenon has been attributed to various aspects of pathophysiology that prevent glioblastoma cells from infiltrating and surviving beyond the intra‐cranial environment. We report a case of IDH‐wild type glioblastoma with extracranial metastasis in submandibular region.