Peritoneal Fluid Cytology of Disseminated Large Cell Neuroendocrine Carcinoma Combined with Endometrioid Adenocarcinoma of the Endometrium

Abstract

© 2019 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/ by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 2383-7837 eISSN 2383-7845 Primary large cell neuroendocrine carcinoma (LCNEC) of the endometrium is extremely rare and the cytomorphology has not been well described. Recently, we experienced a case of combined LCNEC with endometrioid carcinoma (ECa) showing peritoneal dissemination that was confirmed by histology and peritoneal fluid cytology. The purpose of this report is to delineate cytologic characteristics of LCNEC in an effusion specimen.