Gastrointestinal stromal tumor: Retrospective evaluation of twenty cases

Abstract

DOI: 10.4328/ACAM.20658 Received: 2021-04-14 Accepted: 2021-07-28 Published Online: 2021-08-10 Corresponding Author: Deniz Öçal, Department of Gastroenterology Surgery, Erzurum Regional Education and Research Hospital, Erzurum, Turkey. E-mail: [email protected] P: +90 505 297 33 30 Corresponding Author ORCID ID: https://orcid.org/0000-0002-8084-8866 Abstract Aim: In this study, we aimed to evaluate the clinico-pathological findings and treatment methods of 20 cases operated for intra-abdominal gastrointestinal stromal tumor. Material and Methods: The data of 20 cases operated at Erzurum Regional Education and Research Hospital, Erzurum, Turkey between 2015 to 2020 were retrospectively analyzed. Gastrointestinal stromal tumor (GIST) locations, surgical methods, histopathological diagnosis, postoperative medical treatments were discussed. Results: Eleven (55%) patients were male, and nine (45%) were female, and the mean age of all patients was 57.7 ± 11.42 (39-76) years. Most of the tumor was in the stomach (70%). Abdominal pain and bleeding were the main symptoms at admission. The mean diameter of the tumors was 61.5 ± 30.3 mm (10120 mm). The most common surgical technique was laparoscopic gastric wedge resection in 7 patients (35%). Seven patients were classified as high risk, 6 as medium risk, 5 as low risk and 2 patients as a very low risk on pathological evaluation. CD117 expression was positive in all patients, and CD34 expression was found to be positive in 15 (75%) patients. Discussion: Gastrointestinal stromal tumors are mainly located intraabdominally. The most common symptoms are abdominal pain and bleeding. Symptoms depend on the location of the tumor in the abdomen. The main purpose of surgery is the complete resection of the mass performed with a negative surgical margin. Minimally invasive methods can be applied safely in GISTs.