UMA BREVE SÍNTESE DO CENÁRIO ATUAL DOS MEDICAMENTOS E TERAPIAS ANTIRRETROVIRAIS PARA O COMBATE AO HIV NO BRASIL

Abstract

HIV (Human Immunodeficiency Virus) had its first description in the early 1980s, being referred to as a retrovirus capable of transcribing its ribonucleic acid (RNA) genome into a double-stranded deoxyribonucleic acid (DNA) molecule, prior to the integration of the virus genome into the host cell chromosome. In the same period, antiretroviral therapy (ART) began to be developed as a means of combating the progress of the disease in patients who had the virus. Thus, the present work has as main objective to present the drugs and treatments currently offered in Brazil to combat HIV through the so-called ART. For this, the methodology chosen for the development of this research was that of bibliographic-descriptive. The collected results show that Brazil has the following classes of drugs as antiretroviral therapies: Protease inhibitors (IP) Nucleoside / Nucleotide analog reverse transcriptase inhibitors (INTR / INTRt) Non-nucleoside analog reverse transcriptase inhibitors (INNTR) Inhibitors input (IE) Integrase Inhibitors (INI). In addition, the causes of therapeutic failures and how the use of these drugs in antiretroviral regimens is associated with an improvement in the quality of life of HIV patients will also be analyzed.