Factores Asociados a la no adherencia del tratamiento Antirretroviral en Pacientes con VIH en un hospital de Paraguay

Abstract

Background:\xa0Highly active antiretroviral therapy (HAART) is the basis of treatment for patients with human\xa0immunodeficiency virus (HIV) infection and, today, the main concern regarding HIV control is effective adherence\xa0to treatment, for effective treatment and appropriate evaluation of therapeutic regimens in order to carry out\xa0corrective and strategic measures. \nAim:\xa0Identify the associated factors to the lack of adherence to antiretroviral treatment in HIV patients that\xa0attend to the National Hospital of Itaugua on September 2016 \nMethods:\xa0Observational and analytical study, transverse cut, non-probabilistic sampling of consecutive cases.\xa0The study included 42 HIV patients under antiretroviral treatment of the Itaugua National Hospital. It used a\xa0demographic questionnaire and the SMAQ test to evaluate the treatment adherence. For data analysis, it was\xa0used Odd Ratio and p<0,05 was considered as significant. \nResults:\xa036 patients (86%) showed non-adherence to their treatment. It was found a significant association\xa0with adverse effects presence (OR: 8.29, IC95%: 1.25-54.71, p=0.044) and forgetting to take their medicine on\xa0weekends (OR:28.82, IC95%: I.45-556.I, p=0.003). \nConclusion:\xa0The rate of non-adherence to antiretroviral treatment in patients was high, and the associated\xa0factors were the presence of adverse effects and forgetting to take the medication on weekends.