To Assess Outcome of NSTEMI Patients with Raised Serum Uric Acid Level

Abstract

Background: Few studies investigated serum uric acid with short and long-term major adverse outcome (MACE) in patients with NSTEMI. Non-ST Segment Elevation Myocardial Infarction (NSTEMI) is the common form of ACS and a leading global cause of premature morbidity and mortality. Objective: To assess in-hospital outcome of NSTEMI patients with raised serum uric acid level. Methodology: This was a cross-sectional observational study that was conducted in the Department of Cardiology, Manipal AFC Hospital, Khulna during the period from January, 2019 to June, 2020. Purposive consecutive sampling of 55 cases of NSTEMI with raised SUA level and 55 cases of NSTEMI with normal SUA level who were admitted in CCU included in this study. In-hospital complications and mortality were recorded while continuing standard treatment for the event. Results: The study population was between 30-80 years. Only 20 (18.18%) patients were below 40 years. The mean age of patients was 55.4 ±11.4 years. The mean age of the patients of group A was significantly higher than patients of Group B (p<0.001). Male preponderance was in both groups (81.8% versus 78.0%; p=0.603). Diabetes mellitus (52.7% versus 21.8%; p=0.002), hypertension (78.1% versus 52.7%; p=0.039) and dyslipidaemia (47.2% versus 12.7%; p<0.001) were more frequent in group A than that of group B. The mean BMI of patients was 25.72±1.99 kg/m2. Mean systolic BP was 126.61±21.86 mm of Hg and diastolic BP was 82.07±13.11 mm of Hg. But smoking status (69.0% versus 65.4%; p=0.668)