Clinical and laboratory predictors of progression of chronic kidney disease

Abstract

Aim. To present the clinical and functional characteristics of chronic kidney disease at the hospital stage.Material and methods. The material for the study included retrospective analysis of medical records (case histories, statistical card, individual cards) of patients with a diagnosis of CKD who were admitted to the nephrology department of the NMCShifobakhsh (clinical base of the Department of Internal Medicine) in Dushanbe for the period 2018 to - 2020. All patients underwent laboratory and instrumental examinations.Results. During the study period, n=680 patients with a diagnosis of CKD (n=251 men and n=429 women) were hospitalized. Among the reasons for the development of CKD, the most frequent were diabetic nephropathy - 45.9%, Arterial Hypertension - 27.9%, and glomerulonephritis - 18.1%. The majority of patients with CKD are represented by the age categories 60–70 years (38.1%) and 50–60 years (28.2%). Obesity was observed in 37.1%, overweight in 38.7%, and normal body weight in 24.2% of patients.Conclusion. A retrospective analysis of medical records revealed a high frequency of inpatients with DN in the structure of CKD, which characterizes inadequate metabolic control and low adherence to hypoglycemic drugs. Assessment of RF and comorbidities revealed several features depending on gender, as well as the presence of high cardiovascular risk in patients with CKD.