Potential of Gene editing and RNAi in SARS-Cov-2 diagnosis and therapy

Abstract

SARS-CoV-2 surveillance is important to controlling widespread transmission and contains the disease in small peaks. Although mask and vaccination are playing definite role in the prevention of disease but significant work is required in both novel diagnostics and therapeutics. Scientific community is globally working tirelessly to address this gap at the earliest. SARS-CoV-2 is closely related to beta coronavirus species and subspecies; therefore, the detection assays may generate the false-positive results if test are not specifically designed against SARS-CoV-2. Secondly, patient may develop a simultaneous co-infection with other virus. The Confirmation of the COVID-19 is by virus isolation followed by RT-PCR and sequencing. This led to newer classification scheme recently given by WHO to avoid geopolitical controversies and develop consensus. (01).