Discrepancies between self-reported and device-measured sleep parameters in adults with multiple sclerosis.

Abstract

STUDY OBJECTIVES\nSleep problems are a common consequence of multiple sclerosis (MS); however, there is limited evidence regarding the agreement between device-measured and self-reported sleep parameters in adults with MS. The present study examined the agreement between self-reported and device-measured parameters of sleep quality in a sample of adults with MS.\n\n\nMETHODS\nParticipants (N=49) completed a seven-day sleep diary and wore a wrist-worn ActiGraph GT3X+ for seven consecutive nights to quantify self-reported and device-measured sleep parameters, respectively.\n\n\nRESULTS\nThere was a significant discrepancy between self-reported and device-measured parameters of total time in bed (mean difference=19.8(51.3) min), sleep onset latency (mean difference=22.2(19.5) min), and frequency of awakenings during the night (mean difference=12.8(6.8)). Intraclass correlation (ICC) estimates indicated poor agreement between methods on most parameters, except for total time in bed (ICC=0.80). Bland-Altman plots suggested that total time in bed and total sleep time had acceptable levels of agreement and linear regression analyses indicated that sleep onset latency (F=113.91, B=-1.34, p<0.001), number of awakenings (F=543.34, B=1.85, p<0.001), and sleep efficiency (F=18.39, B=-0.77, p<0.001) had significant proportional bias.\n\n\nCONCLUSIONS\nOur results draw attention to the discrepancies between sleep parameter measurements and highlight the importance of including both self-report and device-measured outcomes for a complete and accurate representation of sleep in adults with MS.