Juvenile Nasopharyngeal Angiofibroma

Abstract

Juvenile Nasopharyngeal Angiofibroma (JNA) remains one of the most enigmatic tumors encountered by laryngotologists-head neck surgeons. Its origin at a particular age in a particular sex has intrigued many. Histopathologically benign, JNAs are locally aggressive tumors with tendency to cause massive recurrent nasal bleeds. While surgery remains the gold standard treatment, a paradigm shift from open approaches to endoscopic approach is noted. Recent advances in genomic testing, radiodiagnosis and endoscopic nasal surgeries allow us to manage these tumors more efficiently. Introduction of intensity modulated radiotherapy (IMRT), stereotactic surgery, and interventional radiology (embolisation) has further helped in this cause. This chapter aims to give a brief overview of all these aspects related to JNA with the hope to initiate more ENT surgeons to contribute to further research on this benign but dangerous tumor.