The Analysis of the Factors affecting Medication Adherence in Patient with SLE (Systemic Lupus Erythematosus) at Yayasan Tittari Griya Kupu Solo

Abstract

The prevalence of systemic lupus erythematosus (SLE) in Indonesia was considered high (approach 100.000/year). Medication adherence was essential for the control of symptoms and progression of SLE. This study aimed to measure the prevalence of medication adherence and analyze associations between socio-demographic, duration disease, number of currently used medicines and side effects of medication adherence in patients with SLE. The research used descriptive, analytic method held from February 2018 to April 2018 with the total of 41 respondents. The data were collected through questionnaire and individual interviews. Medication adherence was assessed by interviews based on the Morisky Green Levine Scale (MGLS), and the associated factors (gender, age, level of education, occupation, income, duration of disease, number of currently used medicines, and side effect) were analyzed using chi-square test. Twenty-two patients (53, 65%) were using combination drug while 19 patients (46, 34%) were using a single dosage form. The percentage of patients classified as non-adherence to treatment was 36.6%. The chi-square analysis of characteristics of the patient and medication adherence showed that there was a significant relationship between side effect (p-value 0, 025) with medication adherence. There was no significant relationship between medication adherence with gender, age, level of education, occupation, income, duration of disease and number of currently used medicines (p>0, 05). It can be concluded that the incidence of side effect is a significant predictor of medication adherence for a patient with SLE.