Anuric Acute Kidney Injury Due to Infection-related Glomerulonephritis Secondary to Foot Osteomyelitis

Abstract

We report the case of a 76-year-old male who developed anuric acute kidney injury from infection-related glomerulonephritis (IRGN) secondary to foot osteomyelitis, confirmed via renal biopsy. The patient initially presented with wound dehiscence of the left foot following transmetatarsal amputation and Lisfranc operation in the setting of osteomyelitis. Hospitalization was complicated by worsening acute kidney injury requiring the initiation of hemodialysis. Despite successful surgical correction and the removal of the infectious source, the patient was unable to regain significant renal function and remained hemodialysis dependent. This case highlights a rarely seen complication of osteomyelitis and underscores the value of prompt and aggressive management of osteomyelitis in patients with infection-related glomerulonephritis.