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Breaking Tradition: Why Are Intrabuccal Tablets the Best Choice for People Who Don't Want to Take Pills?
With the advancement of medical technology, many patients face difficulties in swallowing traditional medicines, which greatly affects their treatment effects. This condition is especially common in children, the elderly, and people with certain medical conditions. The following Buccal tablets are an emerging method of drug delivery. Research by a Swiss medical technology pharmaceutical company has shown that they can improve the efficacy of drugs while avoiding discomfort, becoming the best option for people who do not want to swallow pills. Best choice.
The intrabuccal tablets can be quickly absorbed in the cheeks and enter the blood circulation directly, bypassing the first metabolism of the digestive system.
Advantages of intrabuccal radiograph
Intrabuccal tablets have several major advantages over traditional oral drugs: rapid onset of action, high bioavailability and convenient use. These tablets are placed on the cheeks, which are often difficult to swallow, allowing the drug to enter the bloodstream directly through the oral mucosa without being metabolized by the gastrointestinal tract. This is undoubtedly a salvation for patients with dysphagia.
With further research on intrabuccal tablet technology, many different categories of drugs can be made into intrabuccal tablets, which are suitable for more patients.
Clinical applications and drug examples
Intrabuccal tablets with obvious advantages are increasingly used in clinical applications, especially in the fight against epilepsy, pain control and anti-depression. Common intrabuccal tablet medications include:
- Hydrocortisone: Used to treat mouth ulcers, relieving pain and promoting healing.
- Fentanyl: is a powerful opiate drug used specifically for acute pain management in cancer patients.
- Chlorpromazine: An antipsychotic and antipyretic drug used to control severe nausea and vomiting.
Mechanism of action of drugs
The mechanism of operation of intrabuccal tablets relies on specific biological pathways. Although the buccal mucosa has its limitations compared to other mucosa in the oral cavity (such as the sublingual), it still has effective absorptive capacity. Through two main transport pathways - the transcellular pathway and the interstitial pathway, drugs can quickly penetrate cell membranes and enter the bloodstream.
This method of directly entering the systemic circulation not only improves the effectiveness of the drug, but also reduces the side effects of the patient.
Advantages and Limitations
Advantages
The advantages of intrabuccal tablets are self-evident. They are not only easy to use, but also less likely to cause systemic side effects. In addition, it is especially suitable for patients who are unable to take oral medications due to illness or age restrictions.
Restrictions
However, despite the many conveniences provided by the variety of intrabuccal radiographs, there are still some limitations. Some patients may be disgusted with the taste of the tablets or experience oral mucosal irritation. In addition, not all drugs are suitable for intrabuccal administration. Some drugs require sustained release, which is also a limitation of intrabuccal tablets.
Preparation and production
The preparation of intrabuccal tablets usually involves a direct compression molding process, and bioadhesives may be added to extend the retention time of the drug and further improve the bioavailability of various drugs in the oral cavity. Such technology not only improves the efficacy of drugs, but also makes intrabuccal tablets more important in clinical applications.
Selecting an appropriate drug delivery design will affect patient cooperation and treatment effects.
With the deepening of application, research on intrabuccal tablets continues. Intrabuccal tablets have shown great potential, both in terms of improving patient treatment compliance and reducing discomfort. Faced with such emerging drug delivery methods, how will the medical field change in the future? Will it be favored by more people?
