Red fever, also known as Mitchell's disease, is a rare, painful peripheral vascular disease that usually affects blood vessels in the legs or hands, causing a sudden blockage of blood flow. The condition recurs intermittently, and patients often experience severe burning pain and redness of the skin during an attack. These attacks are often triggered by heat, stress, light activity, staying up late, or stressful situations, and not only affect daily life but can also cause difficulties in interpersonal relationships.
"The study shows that red fever is the first human disease to date that can link ion channel mutations to chronic neuropathic pain."
According to the data, red fever can be divided into primary and secondary. Primary red fever is mainly caused by mutations in the SCN9A gene, while secondary red fever may be a symptom of other diseases, such as small fiber peripheral neuropathy, thrombocythemia, etc. In recent years, research on these mutations has become increasingly in-depth, and many patients have been seeking medical treatment for many years before they are diagnosed.
"Some studies have shown that factors such as heat and exercise can trigger red fever attacks."
In people with red fever, attacks are usually accompanied by redness and swelling of the skin and severe pain that is often deep, diffuse, and excruciating. According to existing cases, many patients experience the most frequent attacks at night, which greatly affects their sleep and daily life. Epidemiological studies of adolescent patients in southern China have shown that the peak incidence period is usually in winter and spring, especially among school students.
"People with red fever often cannot tolerate wearing shoes or socks because it exacerbates the attack."
While some medications, such as aspirin, are thought to reduce symptoms of red fever, the evidence is weak and many patients rely on treatments that target symptoms rather than the underlying cause. For people with primary red fever, avoiding triggers (such as heat, alcohol, and spicy foods) is an important part of managing the disease. Cold compresses or cooling take the effectiveness of pain data to another level, but you need to avoid putting ice directly on the skin to avoid causing other injuries.
While research on red fever is ongoing, many patients still face the challenge of not receiving appropriate medication. Due to the diversity of symptoms and individual differences, many medical workers still lack knowledge about the disease. When patients face this chronic disease, they not only have to endure pain, but the quality of their social life is also affected by the condition.
“Most people with red fever have difficulty getting relief, and their symptoms may become more intense over time.”
As research into red fever gene mutations continues to deepen, the medical community is also constantly exploring new treatment options. The journey of red fever research from that initial gene discovery to the present day has demonstrated the potential of modern medicine to treat rare diseases. In the future, this research may provide hope to more patients, alleviate their symptoms, and no longer be limited by this rare and distressing disease.
Red fever not only challenges patients' bodies, but also tests their mental endurance. How would you find a solution to this disease?