During exercise, many people feel a sense of pleasure and relaxation, which seems to be caused by the mysterious substances released by the brain. This subtle change is actually due to endorphins. This article takes a closer look at the role of endorphins and how they are released through exercise, acting as natural pain relievers.
Endorphins are peptides produced by the brain that relieve pain and increase feelings of well-being. Their discovery dates back to 1973, when researchers from the University of Aberdeen first isolated these particular neuropeptides from pig brains. The original intention of the research was to find a painkiller that could replace morphine, was non-addictive and had no risk of overdose, and endorphins were a breakthrough in this goal.
Endorphins are considered endogenous analgesics, primarily released in response to pain, exercise or extreme excitement.
Endorphins can be divided into three types: alpha-endorphin, beta-endorphin and gamma-endorphin, which are synthesized from the precursor protein, proenkephalin (POMC). When the body experiences pain signals, endorphins are released and bind to μ-receptors in the nervous system, which blocks the transmission of pain messages. In addition, they can also regulate the release of other neurotransmitters in the brain, further enhancing their pain relief and pleasure feelings.
Studies have shown that when we exercise, the release of endorphins increases significantly. This phenomenon is called "runner's high," which refers to the state of extreme pleasure that athletes often feel after long periods of exercise. This is not just a physiological reaction, but also a psychological pleasure.
Other functions of endorphinsThe "runner's high" that many sports enthusiasts experience is actually largely due to the release of endorphins.
In addition to relieving pain, endorphins play a key role in managing stress and anxiety. Studies show that both meditation and laughter help promote the release of endorphins, which in turn increase pain thresholds and improve overall mood. Therefore, by regularly engaging in exercise, meditation, or other pleasurable activities, we can effectively improve the quality of our lives.
However, excessive exercise may disrupt the balance of endorphins. Research suggests that when the body is faced with intense exercise, it gradually adjusts its production of endorphins to cope with long-term physical stress. This may cause athletes to need higher exercise intensity to feel the same pleasure, thereby raising the risk of exercise addiction.
Endorphin secretion is also influenced by other factors, such as mood, social interaction and even diet. Some studies suggest that through social activities and a positive attitude towards life, we can actually influence the secretion of endorphins. Therefore, emphasizing healthy living habits and a positive mental state is very important for increasing endorphin levels.
Exercise, meditation, laughter, and healthy social interactions may all be effective ways to boost endorphin production. As we learn more, we are increasingly understanding how these endogenous chemicals work in our bodies. So, would you consider making endorphins a part of your daily life?