A. Completo

Straight, semi-anatomic and anatomic TMJ implants: The influence of condylar geometry and bone fixation screws

A 3D finite element model of in vitro intact and implanted mandibles with different temporomandibular joints (TMJ) was analyzed. Three TMJ implant geometries were assessed. The displacements, stress and strain fields on the condyle were obtained for both simulated cases. Strains were also assessed near the screws that fixate the implant to the mandible. The geometry of the mandible was obtained through 3D digitalization of a synthetic model. The TMJ implants studied were modelled considering a commercial implant which was also used to create semi-anatomic and anatomic implants that were analyzed and to assess the influence of the geometry. Numerical finite element models were built and the implants were positioned by an experienced orofacial surgeon. All implants were fixed by four screws which were placed in the same position on the mandible. The boundary conditions were simulated considering the support on the incisive tooth, the loads of the five most important muscular forces and a 5mm mouth aperture. This study indicates that the deformation on the intact mandible was similar when an anatomic implant was considered in the implanted mandible. However, the anatomic geometry presented some problems concerning the implant integrity due to geometric variations. The geometry of TMJ implant also played a role relatively to the screws structural integration and bone fixation. The geometry of TMJ implant defines the necessary number of screws and position in the mandible fixation.

The influence of different tibial stem designs in load sharing and stability at the cement–bone interface in revision TKA

Total Knee Arthroplasty (TKA) changes mechanical loading of the knee joint. Bone loss in the tibia is commonly encountered at the time of the revision TKA. Restoration of lost bone support and joint stability are the primary challenges in revision TKA. Normally, these defects are treated with non-living structures like metallic augments or bone grafts (autografts or allografts). Alone, neither of these structures can provide the initial support and stability for revision implants. In the latter, the use of intramedullary stems can provide the necessary load sharing and protect the remaining host bone and graft from excessive stress, increasing component stability. The purpose of this study was to evaluate comparatively load sharing (cortical rim, cancellous bone and stem) and stability at the cement-bone interface under the tibial tray induced by the use of cemented and press-fit tibial component stem extensions. Furthermore the study of the desirable option in cases where the bone defect is cavitary (cancellous bone defect contained by an intact cortical rim) or uncontained bone defect (bone loss involving the supporting cortical rim) was carried out. Because in vitro evaluation of these biomechanical parameters is difficult we used finite element (FE) models to overcome this. The biomechanical results suggest an identical behaviour in case of cavitary defects for both types of stems assessed. In the case of uncontained defect treated with bulk allografts the cemented stem may be a prudent clinical option.

Finite Element and Experimental Cortex Strains of the Intact and Implanted Tibia

Finite Element (FE) models for the simulation of intact and implanted bone find their main purpose in accurately reproducing the associated mechanical behavior. FE models can be used for preclinical testing of joint replacement implants, where some biomechanical aspects are difficult, if not possible, to simulate and investigate in vitro. To predict mechanical failure or damage, the models should accurately predict stresses and strains. Commercially available synthetic femur models have been extensively used to validate finite element models, but despite the vast literature available on the characteristics of synthetic tibia, numerical and experimental validation of the intact and implant assemblies of tibia are very limited or lacking. In the current study, four FE models of synthetic tibia, intact and reconstructed, were compared against experimental bone strain data, and an overall agreement within 10% between experimental and FE strains was obtained. Finite element and experimental (strain gauge) models of intact and implanted synthetic tibia were validated based on the comparison of cortex bone strains. The study also includes the analysis carried out on standard tibial components with cemented and noncemented stems of the P.F.C Sigma Modular Knee System. The overall agreement within 10% previously established was achieved, indicating that FE models could be successfully validated. The obtained results include a statistical analysis where the root-mean-square-error values were always <10%. FE models can successfully reproduce bone strains under most relevant acting loads upon the condylar surface of the tibia. Moreover, FE models, once properly validated, can be used for preclinical testing of tibial knee replacement, including misalignment of the implants in the proximal tibia after surgery, simulation of long-term failure according to the damage accumulation failure scenario, and other related biomechanical aspects.

Strain shielding in distal femur after patellofemoral arthroplasty under different activity conditions.

Strain shielding, a mechanical effect occurring in structures combining stiff with more flexible materials, is considered to lead to a reduction of density in bone surrounding the implant. This effect can be related to the weakness of the implant fixation, which can promote implant loosening. Several studies describe a significant decrease in postoperative bone mineral density adjacent to joint implants, which can compromise their long-term fixation. The aim of the present study was to quantify the strain shielding effect on the distal femur after patellofemoral arthroplasty. For this purpose three activities of daily living were considered: level walking, stair climbing and deep bending at different angles of knee flexion. To determine the strain shielding effect, cortical bone strains were measured experimentally with triaxial strain gauges in synthetic femurs before and after patellofemoral arthroplasty for each of the different daily activities. The results showed that the patellofemoral arthroplasty in general reduced the strains in the medial and distal regions of the femur when deep bending activity occurred, consequently, strain shielding in these regions, with strain decreases of -72.0% and -67.5% were measured. On the other side, higher values of strain were found in the anterior region after patellofemoral replacement for this activity with an increase of +182.0%. The occurrence of strain shielding seems to be more significant when the angle of knee flexion and applied load increases. Strain shielding and over-loading may have relevant effects on bone remodeling surrounding the patellofemoral implant, suggesting a potential effect of later bone resorption in the medial and distal femur regions in case of regular deep bending activity.

Biomechanical evaluation of proximal tibia behaviour with the use of femoral stems in revision TKA: An in vitro and finite element analysis

BACKGROUND Recognized failure mechanisms after revision total knee arthroplasty include failure of fixation, instability and loosening. Thus, extended stems have been used to improve fixation and stability. In clinical cases where the stem is only applied in the femur, a question concerning the structural aspect of tibia may arise: Does a stemmed femur changes the structural behaviour of proximal tibia? It seems, that question has not yet been fully answered and the use of stems in the opposite bone structure requires further analysis. METHODS Proximal cortex strains were measured with tri-axial strain gauges in synthetic tibias for three different types of implanted femurs, with two constrained implants. To assess the strains at the cancellous bone under the tibial tray, it was considered a closest physiological load condition with the use of finite element models. FINDINGS No significant differences of the mean of the tibial cortex strains for the stemmed femur relatively to the stemless femur were observed. The R(2) and slopes values of the linear regressions between experimental and finite element strains were close to one indicating good correlations. The strain behaviour of cancellous bone under the tibial tray is not completely immune to the use of femoral stem extensions. However, the level of this alteration is relatively small when compared with the strain magnitudes. INTERPRETATION The main insight given by the present study could probably lie in the fact that the use of femoral stems does not contribute to an increase of the risk of failure of the tibia.

Influence of the contact model on the dynamic response of the human knee joint

The goal of this work is to study the influence of the contact force model, contact geometry, and contact material properties on the dynamic response of a human knee joint model. For this purpose, a multibody knee model composed by two rigid bodies, the femur and the tibia, and four non-linear spring elements that represent the main knee ligaments, is considered. The contact force models used were the Hertz, the Hunt–Crossley, and the Lankarani–Nikravesh approaches. Results obtained from computational simulations show that Hertz law is less suitable to describe the dynamic response of the cartilage contact, because this pure elastic model does not account for the viscoelastic nature of the human articulations. Since knee can exhibit conformal and non-conformal contact scenarios, three different geometrical configurations for femur–tibia contact are considered, that is convex–convex sphere contact, convex–concave sphere contact, and convex sphere–plane contact. The highest level of contact forces is obtained for the case of convex–convex sphere contact. As far as the influence of the material contact properties is concerned, the dynamic response of a healthy and natural knee is analysed and compared with three pathological and two artificial knee models. The obtained results demonstrate that the presence of the cartilage reduces significantly the knee contact forces.

Biomechanical evaluation of different reconstructive techniques of proximal tibia in revision total knee arthroplasty: An in-vitro and finite element analysis

BACKGROUND Bone loss and subsequent defects are often encountered in revision total knee arthroplasty. In particular, when the cortical rim of proximal tibia is breached, the surgical decision on the reconstructive options to be taken is challenging due to the variety of defects and the lack of data from clinical or experimental studies that can support it. The purpose of this study is to assess how different reconstructive techniques, when applied to an identical defect and bone condition, can be associated to dissimilar longevity of the revision procedure, and the role of a stem in this longevity. METHODS Proximal cortex strains and implant stability were measured in ten reconstructive techniques replicated with synthetic tibiae. The cancellous bone strains under each construct were assessed with finite element models which were validated against experimental strains. FINDINGS The measured strains and stability showed that the proximal cortex is not immune to the different reconstructive techniques when applied to an identical defect. The largest cancellous strain differences between modular and non-modular techniques indicate a distinct risk between reconstructive techniques, associated to the supporting capacity of cancellous bone at long term. INTERPRETATION The main finding of the present study is the observation that modular augments increases, on a long term basis, the potential risk of bone resorption relative to the non-modular techniques. In addition, the use of a press-fit stem in the scope of non-modular techniques can lead to improved stability and load transfer, which can contribute positively to the life expectancy of these techniques.

A new press-fit stem concept to reduce the risk of end-of-stem pain at revision TKA: A pre-clinical study

PURPOSE Revision total knee arthroplasty presents numerous technical challenges, with lower patient outcomes compared with those obtained in primary surgery. Extended stems have been used in revision total knee arthroplasty to improve component alignment and fixation. Hybrid fixation with cemented tibial tray and press-fit stem has shown good results. One of the disadvantages of this technique is pain related to the presence of a cementless diaphyseal engaging stem, often designated as end-of-stem pain. Patients with this pain have reported a decrease in overall satisfaction, as well as demonstrate a lower clinical outcome score. Clinical findings suggest that stem material and design are important factors in the development of end-of-stem pain. Therefore, a question can be raised: can a novel press-fit stem concept minimize bone strain changes at the stem tip? The hypothesis here considered lies upon the fact, that if periosteal cortex strain changes are minimized at the stem tip comparatively to the intact situation, the risk of end-of-stem pain might be minimized. SCOPE This pre-clinical study was accomplished using synthetic tibiae to experimentally predict the periosteal cortex strains at the proximal and stem tip regions, with a commercial press-fit stem and a new stem concept. CONCLUSIONS The results demonstrated that the new stem concept has the ability to minimize strain changes induced by the stem tip at the distal periosteal cortex and consequently, at the periosteal layer of bone tissue, which is highly pain sensitive, probably contributing to the reduction of the risk of end-of-stem pain.

A systematic approach for an accuracy level using rapid prototyping technologies

Nowadays there has emerged a series of rapid prototyping processes with great potential, and designers and engineers need to know the accuracy performance of these processes to compare and select the best solution. There is a significant lack of published data related to rapid prototyping processes and feature accuracy. This research was conducted to minimize this gap and provide much needed accuracy in terms of dimensional and geometric information. The methodology includes the summarization of previous studies and definition of a benchmarking part that is composed of elementary shapes representative of different features most likely to be found in a final product. The benchmarking part was controlled in terms of dimensional accuracy, geometric precision and freeform deviation. The sources of errors controlled by the final user were analysed, like Standard Tessellation Language (STL) file format resolution and build direction. Four custom rapid prototyping processes have been used and compared: stereolithography, selective laser sintering, fused deposition modelling and three-dimensional printer. Computer numerically controlled machining has been used as an alternative prototyping process in this study as a standard to compare costs and accuracy. This work assessed measures that can be used to quantify the accuracy performance for a given part so that the choices for prototyping can be made based on scientific knowledge and best working practices. These results are very useful for designing products to be prototyped or manufactured through direct methods. The results can be used to improve the functionality of prototypes and the decision process through the best systematic approach.

Biomechanical analysis of total elbow replacement with unlinked iBP prosthesis: An in vitro and finite element analysis

BACKGROUND Numerous models of elbow prostheses are being used and can be divided into two categories: one being a semi-constrained, linked type; and the other being non-constrained, unlinked type. Recent reports of National Elbow Arthroplasty Registers reveal no significant differences in the survival rates between linked and unlinked prosthesis brands, and the main cause appointed for revision for both types is loosening. Some previous biomechanical studies confirm the presence of abnormal bone stresses for the linked type, which can be associated with the risk of loosening. However for the unlinked type, biomechanical studies are not available that corroborate a loosening risk. It seems, that issue has not yet been fully answered and requires further analysis. METHODS Cortex strains adjacent to the elbow joint were measured with strain gauges in synthetic humeri and ulnae, before and after replacement. To assess cancellous bone strains and cement stresses around the implant finite element models validated relative to measured strains were used. FINDINGS Bone strains adjacent to the implant tip increased several times in the humerus and ulna. At the epiphyseal regions a generalised cancellous bone strain reduction was observed for both humerus and ulna relatively to the intact bones. INTERPRETATION The unlinked elbow prostheses can be associated with the risk of bone fatigue failure by overload, particularly in the ulna, and bone resorption by stress-shielding at the epiphyseal regions. The identical structural behaviour relative to linked prostheses associated with the same loosening risks corroborates the results of recent arthroplasty published register reports.