A. Gallini

Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.

Background  Oral 8‐methoxypsoralen–UV‐A (PUVA) and narrowband UV‐B (NB‐UVB or UVB TL‐01) are effective and widely used treatments for chronic plaque psoriasis. Although the role of PUVA therapy in skin carcinogenesis in humans with psoriasis has been clearly demonstrated, there is still controversy regarding the risk of skin cancer with NB‐UVB. Furthermore, there is no clear evidence about the maximum cumulative number of sessions not to be exceeded in a lifetime.

Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.

Background/Aim  To define practical use and to specify the ideal method for monitoring the liver toxicity of MTX in the management of psoriasis.

Adherence to topical treatment in psoriasis: a systematic literature review

Background  Treatment adherence has been recognized as an important issue in the management of chronic diseases such as psoriasis.

Oral cyclosporin in psoriasis: a systematic review on treatment modalities, risk of kidney toxicity and evidence for use in non-plaque psoriasis.

Background  Although cyclosporin (CyA) has been in use in psoriasis for more than 20 years, there is still controversy regarding treatment strategy, monitoring of kidney function and utility in non‐plaque psoriasis.

Evidence-based recommendations on conventional systemic treatments in psoriasis: systematic review and expert opinion of a panel of dermatologists.

Background  There is a high level of heterogeneity regarding the practical use of conventional systemic treatment in psoriasis.

Efficacy of Psoralen UV‐A therapy vs. Narrowband UV‐B therapy in chronic plaque psoriasis: a systematic literature review

Background  Oral 8‐methoxypsoralen‐UV‐A (PUVA) and Narrowband UV‐B (NB‐UVB or UVB TL‐01) are well established treatments for chronic plaque psoriasis but there is limited evidence regarding their respective efficacy.

Evidence-based recommendations on topical treatment and phototherapy of psoriasis: systematic review and expert opinion of a panel of dermatologists

Background  Although topical treatments and phototherapy are available for more than 40 years, there is a paucity of evidence‐based recommendations regarding their use.

Topical corticosteroids in plaque psoriasis: a systematic review of risk of adrenal axis suppression and skin atrophy

Background  Topical steroids have been used for more than 50 years in mild‐to‐moderate plaque psoriasis and carry a theoretical risk of adverse events.

Topical vitamin D analogues alone or in association with topical steroids for psoriasis: a systematic review

Objective  The objective of this systematic review was to prepare for evidence‐based recommendations on the use of vitamin D analogues, and their combination with topical steroids in psoriasis.

Topical corticosteroids in plaque psoriasis: a systematic review of efficacy and treatment modalities

Introduction  Topical steroids are used for more than 50 years to treat mild‐to‐moderate plaque psoriasis. The purpose of this systematic review was to evaluate the efficacy but also the optimal modalities of administration of topical corticosteroids in psoriasis i.e. influence of steroid potency on clinical response, putative impact of topical formulation, occlusion procedure, rate of application to control the initial response and the potential interest of a maintenance treatment to prolong psoriasis clearance.