A. Pane
Boston Children's Hospital
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Publication
Featured researches published by A. Pane.
Journal of Pediatric Surgery | 2012
Erminia Romeo; Vincenzo Jasonni; T. Caldaro; Arrigo Barabino; Girolamo Mattioli; Stefania Vignola; Giovanni Federici di Abriola; Paola De Angelis; A. Pane; Filippo Torroni; Francesca Rea; Luigi Dall'Oglio
BACKGROUND/PURPOSE Surgical resection or strictureplasty (SP) are different options for intestinal Crohn disease (CD) strictures. The aim of this article is evaluation of long-term outcome of SP and resection. METHODS From 1996 to 2011, 39 patients (23 male, 16 female) with symptomatic ileal and ileocolonic CD strictures resistant to medical/nutritional therapy and treated with surgery in 2 different surgical units were reviewed. The mean age at diagnosis was 11.82 years (range, 4-17 years). Mean age at surgery was 15.94 years (range, 4-24 years). Mean follow-up was 6.88 years (range, 0.5-15 years). Patients underwent resection (group A) or different SP techniques (group B). RESULTS Twenty patients underwent intestinal resection (ileal or ileocolonic resection), and 19 patients underwent SP (jejunal, ileal, or ileocolic). Early postsurgical complications were observed in 2 patients of group A. Follow-up of group A patients revealed that 1 patient needed emergency treatment after 8 months surgery because of adhesions and 1 patient developed recurrence treated with medical therapy. In the follow-up group B, 3 patients experienced disease recurrence, 2 of them at the site of previous surgery. CONCLUSIONS At long-term follow-up, no significant difference in relapsing rate was observed between the 2 groups. Strictureplasty and resection represent an effective treatment of pediatric CD strictures. Strictureplasty could represent the first option for intestinal preservation.
Journal of Pediatric Surgery | 2017
Anna Maria Caruso; A. Pane; Roberto Garau; Pietro Atzori; Marcello Podda; Alessandra Casuccio; Luigi Mascia
PURPOSE An accurate diagnosis of acute appendicitis is important to avoid severe outcome or unnecessary surgery but management is controversial. The aim of study was to evaluate, in younger and older children, the efficacy of conservative management for uncomplicated appendicitis and the outcome of complicated forms underwent early surgery. METHODS Children with acute appendicitis were investigated by clinical, laboratory variables and abdominal ultrasound and divided in two groups: complicated and uncomplicated. Complicated appendicitis underwent early surgery; uncomplicated appendicitis started conservative treatment with antibiotic. If in the next 24-48h it was worsening, the conservative approach failed and patients underwent late surgery. RESULTS A total of 362 pediatric patients were included. One hundred sixty-five underwent early appendectomy; 197 patients were at first treated conservatively: of these, 82 were operated within 24-48h for failure. The total percentage of operated patients was 68.2%. An elevated association was found between surgery and ultrasound. CONCLUSIONS Conservative treatment for uncomplicated appendicitis had high percentage of success (58%). Complications in operated patients were infrequent. Our protocol was effective in order to decide which patients treat early surgically and which conservatively; specific red flags (age and onset) can identified patients at most risk of complications or conservative failure. TYPE OF STUDY treatment study. LEVEL OF EVIDENCE II.
Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) | 2018
A. Pane; Luigi Mascia
We report an unusual case of ileal intussusception in a 7-year-old girl affected by Peutz Jeghers syndrome, characterized by a very misleading clinical presentation, resembling chronic constipation. Correct diagnosis was guided through appropriate knowledge of inherited condition and cautious ultrasound monitoring. Confirmation was achieved by a timely surgical intervention and subsequent pathologic examination.
Endoscopy | 2006
Filippo Torroni; P. De Angelis; T. Caldaro; G. Federici; A. Pane; Claudio Romano; L. Dall’Oglio
We report here the case of a 15−year−old patient with symptoms characteristic of intestinal bleeding and severe anemia, who required repeated transfusions. The hematochemical parameters (erythrocyte sedimentation rate, CRP (c−reactive pro− tein), antineutrophil cytoplasmic antibo− dies, anti−Saccharomyces cerevisiae anti− bodies (ASCA), antiendomysium antibo− dies, and the transglutaminases), and esophagogastroduodenoscopy and colo− noscopy examinations, including histolo− gy, were normal.
Digestive and Liver Disease | 2006
P. De Angelis; Jonathan E. Markowitz; Filippo Torroni; T. Caldaro; A. Pane; G. Morino; R. Sforza Wietrzykowska; G. Federici di Abriola; A. Ponticelli; L. Dall’Oglio
Expert Opinion on Pharmacotherapy | 2008
P. De Angelis; G. Morino; A. Pane; Filippo Torroni; Paola Francalanci; T. Sabbi; Francesca Foschia; T. Caldaro; G. Federici di Abriola; Luigi Dall'Oglio
Journal of Pediatric Gastroenterology and Nutrition | 2006
Erminia Romeo; Filippo Torroni; P. De Angelis; A. Pane; T. Caldaro; Salvatore Cucchiara; B. Papadatou; L DallʼOglio
Archive | 2017
Anna Maria Caruso; A. Pane; Andrea Scanu; Alessandro Muscas; Roberto Garau; Franco Caddeo; Luigi Mascia
Journal of Pediatric and Neonatal Individualized Medicine | 2017
Anna Maria Caruso; A. Pane; Andrea Scanu; Alessandro Muscas; Roberto Garau; Franco Caddeo; Luigi Mascia
Digestive and Liver Disease | 2010
Francesca Foschia; Erminia Romeo; Filippo Torroni; P. De Angelis; T. Caldaro; G. Federici di Abriola; A. Pane; Luigi Dall'Oglio