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A. Pekkarinen

University of Turku

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Publication

Featured researches published by A. Pekkarinen.

Archive | 1977

Studies on Pharmacokinetics of N-Demethyldiazepam, the Active Main Metabolite of Diazepam

L. Kangas; J. Kanto; Raija Sellman; A. Pekkarinen

The main metabolite of diazepam (D) in man is N-demethyldiazepam (ND), which, after hydroxylation to oxazepam, is excreted mainly in conjugated form in the urine. The aim of these studies was to get more information about the pharmacokinetics of D and ND, especially in humans, because of wide use of D and scanty knowledge of its metabolism and pharmacokinetics in patients.

Pharmacology & Toxicology | 2009

Human and Animal Study on Elimination from Plasma and Metabolism of Diazepam after Chronic Alcohol Intake

Raija Sellman; J. Kanto; E. Raijola; A. Pekkarinen

Pharmacology & Toxicology | 2009

Pharmacokinetics of nitrazepam in saliva and serum after a single oral dose.

L. Kangas; H. Allonen; Risto Lammintausta; M. Salonen; A. Pekkarinen

Pharmacology & Toxicology | 2009

Induction Effect of Diazepam on its Own Metabolism

Raija Sellman; J. Kanto; E. Raijola; A. Pekkarinen

Pharmacology & Toxicology | 2009

Reduced Concentrations of Plasma Diazepam in Chronic Alcoholic Patients Following an Oral Administration of Diazepam

Raija Sellman; A. Pekkarinen; L. Kangas; E. Raijola

Pharmacology & Toxicology | 2009

Cerebrospinal‐fluid Concentrations of Nitrazepam in Man

L. Kangas; J. Kanto; T. Siirtola; A. Pekkarinen

Pharmacology & Toxicology | 2009

Effect of psychic stress of examination on serum growth hormone, serum insulin, and plasma renin activity.

Erkka Syvälahti; Risto Lammintausta; A. Pekkarinen

Pharmacology & Toxicology | 2009

Dialysability of Benzodiazepines by Haemodialysis and Controlled Sequential Ultrafiltration (CSU) in Vitro

A. Balogh; R. Fünfstück; U. Demme; L. Kangas; H. Sperschneider; A. Traeger; G. Stein; A. Pekkarinen

Pharmacology & Toxicology | 2009

The Combined Effect of Adrenaline and Sodium Chloride on Blood Pressure in Normal Rats

A. J. Aho; M. I. Linna; A. Pekkarinen

Pharmacology & Toxicology | 2009

Enzyme Action on Adrenaline and Noradrenaline. Studies on Heart Muscle in Vitro.

Esko Iisalo; A. Pekkarinen

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J. Kanto

University of Turku

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L. Kangas

University of Turku

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Raija Sellman

University of Turku

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A. J. Aho

University of Turku

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E. Raijola

University of Turku

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M. I. Linna

University of Turku

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Risto Lammintausta

University of Turku

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U. K. Rinne

University of Turku

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Erkka Syvälahti

University of Turku

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Esko Iisalo

University of Turku

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