A. Slaven
University of Birmingham
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Featured researches published by A. Slaven.
Ophthalmic and Physiological Optics | 1991
Richard A. Armstrong; A. Slaven; G.F. Harding
The visual evoked magnetic response (VEMR) was measured over the occipital cortex to pattern and flash stimuli in 86 normal subjects aged 15‐S6 years. The latency of the major positive component (outgoing magnetic field I to the pattern reversal stimulus (P100M) increased with age. particularly after 55 years, while the amplitude of the P100M decreased more gradually over the lifespan. By contrast, the latency of the major positive component to the flash stimulus (P2M) increased more slowly with age after about 50 years, while its amplitude may have decreased in only a proportion of the elderly subjects. The changes in the P100M with age may reflect senile changes in the eye and optic nerve, e.g. senile miosis, degenerative changes in the retina or geniculostriate deficits. The P2M may be more susceptible to senile changes in the visual cortex. The data suggest that the contrast channels of visual information processing deteriorate more rapidly with age than the luminance channel.
Ophthalmic and Physiological Optics | 1991
A. Slaven; C. Degg; Richard A. Armstrong
Different visual stimuli may activate separate channels in the visual system and produce magnetic responses from the human bran which originate from distinct regions of the visual cortex. To test this hypothesis, we have investigated the distribution of visual evoked magnetic responses to three distinct visual stimuli over the occipital region of the scalp with a DC-SQUID second-order gradiometer in an ubshielded environment. Patterned stimuli were presented full field and to the right half field, while a flash stimulus was presented full field only, in five normal subjects. Magnetic responses were recorded from 20 to 42 positions over the occipital scalp. Topographic maps were prepared of the major positive component within the first 150ms to the three stimuli, i.e., the P100m (pattern shift), C11m (pattern onset) and P2m (flash). For the pattern shift stimulus the data suggested the source of the P100m was close to the midline with the current directed towards the medial surface. The data for the pattern onset C11m suggested a source at a similar depth but with the current directed away from the midline towards the lateral surface. The flash P2m appeared to originate closer to the surface of the occipital pole than both the patterned stimuli. Hence the pattern shift (which may represent movement), and the pattern onset C11m (representing contrast and contour) appear to originate in similar areas of brain but to represent different asepcts of cortical processing. By contrast, the flash P2m (representing luminance change) appears to originate in a distinct area of visual cortex closer to the occipital pole.
Archive | 1994
Richard A. Armstrong; A. Slaven
Archive | 1990
Richard A. Armstrong; A. Slaven; Paul L. Furlong; B. Janday; G. F. A. Harding
Archive | 1991
C. Degg; Richard A. Armstrong; A. Slaven; G. F. A. Harding
Archive | 1993
A. Slaven; Richard A. Armstrong
Archive | 1993
A. Slaven; C. Degg; Richard A. Armstrong
Archive | 1993
C. Degg; A. Slaven; J.L. Bedford; Richard A. Armstrong
Archive | 1991
Richard A. Armstrong; A. Slaven; G. F. A. Harding
Archive | 1991
Richard A. Armstrong; C. Degg; A. Slaven