A. Sudalai

Cu(OTf)2: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Copper(II) triflate catalyzes efficiently the three-component condensation reaction of an aldehyde, β-ketoester and urea in acetonitrile to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in high yields. The catalyst exhibited remarkable reusable activity.

CATALYTIC SELECTIVE OXIDATION OF ALKYL ARENES TO ARYL TERT. BUTYL PEROXIDES WITH TBHP OVER RU-EXCHANGED MONTMORILLONITE K10

Abstract A mild and efficient catalytic method for the benzylic oxidation of alkyl arenes to the corresponding tert. butyl aryl peroxides is described using a catalytic amount of reusable solid, RuIII-exchanged Montmorillonite K10 and 70% tert. butyl hydroperoxide (TBHP) as oxidant.

Enantioselective synthesis of (R)-(−)-baclofen via Ru(II)–BINAP catalyzed asymmetric hydrogenation

Abstract A short and efficient enantioselective synthesis of ( R )-(−)-baclofen, a selective GABA B agonist has been described with an overall yield of 26% and 90% ee. Ru(II)–( S )-BINAP catalyzed asymmetric hydrogenations of CC and CO groups constitute the key steps in introducing stereogenic centers into the molecule.

RECENT ADVANCES IN CLAY-CATALYZED ORGANIC TRANSFORMATIONS

(2000). RECENT ADVANCES IN CLAY-CATALYZED ORGANIC TRANSFORMATIONS. Organic Preparations and Procedures International: Vol. 32, No. 1, pp. 1-40.

OsO4-catalyzed amination of silyl enol ethers: enantioselective synthesis of α-amino ketones

Abstract Osmium tetroxide catalyzed asymmetric aminohydroxylation of silyl enol ethers using cinchona alkaloids as chiral ligands and chloramine-T as the nitrogen source affords enantiomerically pure α-amino ketones.

Synthesis of aryl α-keto-acids via the Cu-catalyzed conversion of aryl nitroaldol products

Abstract Cu(II) salts efficiently catalyze the conversion of a variety of aryl nitroaldol products to afford the corresponding aryl α-keto-acids in high yields using 30% aq. AcOH:MeOH (1:1) as the solvent.

Chemoselective Transfer Hydrogenation of Carbonyl Compounds Catalyzed by Macrocyclic Nickel (II)Complex

Abstract Macrocyclic Ni(II) complex, 1, catalyzes efficiently the chemoselective transfer reduction of carbonyl compounds in presence of propan-2-ol / KOH or HCO2H / HCO2NH4 as hydrogen donors to produce the corresponding alcohols in high yield.

Formamide assisted one-pot conversion of aromatic aldehydes into the corresponding nitriles

A single step conversion of aromatic aldehydes (1) into the corresponding nitriles (2) has been achieved in high yields using stoichiometric amounts of hydroxylamine hydrochloride, pyridine and formamide in refluxing xylene.

Regioselective alkylation of phenol with cyclopentanol over montmorillonite K10: An efficient synthesis of 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]propan-2-ol {(S)-penbutolol}

Regioselective alkylation of phenol with cyclopentanol is achieved over Montmorillonite K10 clay, producing 2-cyclopentylphenol, the key intermediate. The synthesis of optically active (S)-penbutolol 1, an important antihypertensive drug, is realized in 5 steps from 2-cyclopentylphenol by employing Sharpless asymmetric dihydroxylation.

Carbenoid transfer to imines: a new heterogeneous catalyticsynthesis of aziridines

A heterogeneous catalytic method for the preparation of trans-aziridines from imines and methyl diazoacetate is described using Rh III - and Mn III -exchanged montmorillonite K10 clays as catalysts.