A. Venkat Narsaiah

[Bmim]BF4 ionic liquid: a novel reaction medium for the synthesis of β-amino alcohols

Epoxides undergo smooth ring-opening with aryl amines in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) ionic liquids under mild and neutral conditions to afford the corresponding β-amino alcohols in excellent yields with high regioselectivity.

An Efficient Knoevenagel Condensation Catalyzed by LaCl3.7H2O in Heterogeneous Medium

Abstract Knoevenagel condensation was carried out in absence of solvent with a mild Lewis acid Lanthanum(III) chloride, to prepare substituted alkenes. A systematic study of the reaction to establish the generality of the method has been undertaken with various aldehydes and active methylene compounds.

Efficient one pot synthesis of nitriles from aldehydes in solid state using peroxymonosulfate on alumina

Abstract In an environmentally benign solvent-free system, aldehydes are rapidly transformed into nitriles using peroxymonosulfate-alumina under microwave irradiation.

[Bmim]PF6 and BF4 ionic liquids as novel and recyclable reaction media for aromatic amination

Abstract Activated aryl halides undergo smooth nucleophilic substitution reactions with secondary amines in 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF 6 ) or 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF 4 ) ionic liquids (ILs) at room temperature to afford the corresponding arylamines in excellent yields under mild and neutral conditions.

An eco-friendly synthesis of electrophilic alkenes catalyzed by dimethylaminopyridine under solvent-free conditions

Electrophilic olefins were synthesized in solvent‐free condition using DMAP (10%mol) as catalyst in excellent yield and E‐geometry. The various aldehydes which are aliphatic, aromatic, and heterocyclics underwent smoothly for Knoevenagel condensation with different active methylene compounds. #IICT Communication No. 030900.

A Facile Method for the Conversion of Oximes and Tosylhydrazones to Carbonyl Compounds with Dess-Martin Periodinane

Abstract A convenient method for the direct conversion of oximes and tosylhydrazones to carbonyl compounds upon treatment with Dess-Martin periodinane/sodium acetate in CH2CI2 is described.

An efficient benzyltriethylammonium chloride catalysed preparation of electrophilic alkenes: a practical synthesis of trimethoprim

The Knoevenagel condensation of carbonyl compounds with active methylene compounds was readily carried out with benzyltriethylammonium chloride as a catalytic agent, under solvent-free conditions to produce olefinic products in high yields: the scope of this protocol is utilised for the synthesis of the antibacterial agent trimethoprim.

Glycerin and CeCl3 · 7H2O: A New and Efficient Recyclable Reaction Medium for the Synthesis of Quinoxalines

Abstract An efficient and environmentally benign process for the synthesis of quinoxalines has been developed using glycerine–cerium chloride as a reaction medium. This method is applicable to a variety of diketones and 1,2-phenylenediamines to afford the corresponding quinoxaline derivatives in excellent yields. The reaction medium was recovered and reused for further reactions without any problem. GRAPHICAL ABSTRACT

Triphenylphosphine–Iodine: An Efficient Reagent System for the Synthesis of Nitriles From Aldoximes

Abstract A wide range of aldoximes were smoothly converted to the corresponding nitriles with triphenylphosphine–iodine. IICT Communication No. 050106.

Mild and Highly Efficient Protocol for the Synthesis of Benzimidazoles Using Samarium Triflate [Sm(OTf)3]

One-pot synthesis of benzimidazole compounds from ortho-phenylenediamine and a variety of aldehydes was developed under mild reaction conditions. All the reactions were carried out in the presence of samarium triflate (10 mol%) in acetonitrile at room temperature.