Aaron M. Kearney
Johnson & Johnson Pharmaceutical Research and Development
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Publication
Featured researches published by Aaron M. Kearney.
Bioorganic & Medicinal Chemistry Letters | 2011
Brad M. Savall; Laurent Gomez; Frank Chavez; Michael P. Curtis; Steven P. Meduna; Aaron M. Kearney; Paul J. Dunford; Jeffery M. Cowden; Robin L. Thurmond; Cheryl A. Grice; James P. Edwards
This report discloses the development of a series of tricyclic histamine H(4) receptor antagonists. Starting with a low nanomolar benzofuranopyrimidine HTS hit devoid of pharmaceutically acceptable properties, we navigated issues with metabolism and solubility to furnish a potent, stable and water soluble tricyclic histamine H(4) receptor antagonist with desirable physiochemical parameters which demonstrated efficacy a mouse ova model.
Tetrahedron Letters | 2010
Aaron M. Kearney; Adrienne M. Landry-Bayle; Laurent Gomez
Archive | 2010
Genesis M. Bacani; Christa C. Chrovian; Wendy Eccles; Anne M. Fourie; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Alejandro Santillan; Virginia M. Tanis; John J. M. Wiener
Archive | 2010
Genesis M. Bacani; Christa C. Chrovian; Wendy Eccles; Anne M. Fourie; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Alejandro Santillan; Virginia M. Tanis; John J. M. Wiener
Archive | 2010
Genesis M. Bacani; Christa C. Chrovian; Wendy Eccles; Anne M. Fourie; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Alejandro Santillan; Virginia M. Tanis; John J. M. Wiener
Archive | 2010
Genesis M. Bacani; Christa C. Chrovian; Wendy Eccles; Anna M. Fourie; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Alejandro Santillan; Virginia M. Tanis; John J. M. Wiener
Archive | 2009
Genesis M. Bacani; Diego Broggini; Eugene Y. Cheung; Christa C. Chrovian; Xiaohu Deng; Anne M. Fourine; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Jimmy T. Liang; Susanne Lochner; Neelakandha S. Mani; Alejandro Santillan; Kathleen C. Sappey; Kia Sepassi; Virginia M. Tanis; Alvah T. Wickboldt; John J. M. Wiener; Hartmut Zinser
Archive | 2009
Genesis M. Bacani; Diego Broggini; Eugene Y. Cheung; Christa C. Chrovian; Xiaohu Deng; Anne M. Fourine; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Jimmy T. Liang; Susanne Lochner; Neelakandha S. Mani; Alejandro Santillan; Kathleen C. Sappy; Kia Sepassi; Virginia M. Tanis; Alvah T. Wickboldt; John J. M. Wiener; Hartmut Zinser
Archive | 2009
Hartmut Zinser; Genesis M. Bacani; Diego Broggini; Eugene Y. Cheung; Christa C. Chrovian; Xiaohu Deng; Anne M. Fourine; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Jimmy T. Liang; Susanne Lochner; Neelakandha S. Mani; Alejandro Santillan; Kathleen C. Sappey; Kia Sepassi; Virginia M. Tanis; Alvah T. Wickboldt; John J. M. Wiener
Archive | 2008
Genesis M. Bacani; Scott D. Bembenek; Wendy Eccles; James P. Edwards; Matthew T. Epperson; Laurent Gomez; Cheryl A. Grice; Aaron M. Kearney; Adrienne M. Landry-Bayle; Alice Lee-Dutra; Kelly J. Mcclure; Taraneh Mirzadegan; Alejandro Santillan
