Abdulaziz S. Alaamer

Characterization of 222Rn and meteorological parameters in Uro houses at South Kordofan state

This study was carried out to assess and map indoor radon concentration and to estimate radiation dose in Uro town in Sudans South Kordofan state. A portable radon meter (RRA-01M-03), equipped with simple sensors of meteorological parameters has been used for carrying out radon measurement. The annual absorbed dose from the corresponding measured radon concentration was calculated using dose rate conversion factors of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). The corresponding annual effective dose and equivalent dose to the lungs were estimated. Measured activity concentrations of 222Rn, annual absorbed dose, annual effective dose and equivalent dose to the lungs were found in the range 20–4482 Bq/m3, 0.32–70.67 mSv/y, 0.76–169.61 mSv−y and 0.16 × 10−7 to 35,856 × 3.5856 × 10−11 mSv−y, with geometric mean 109.43 Bq/m3, 1.73, 4.16 and 1.1 × 10−7 mSv−y, respectively. Upon comparing the results with global data, it was found with the exception of six samples, the obtained values fall far below the action level of 200–600 Bq/m3 recommended by the International Commission on Radiological Protection. However, the geometric mean is higher than the reported average global indoor radon concentration. Meteorological parameters were measured and no correlation was noted between radon concentration and these parameters. The overall annual effective dose was higher than the UNSCEAR recommended reference dose level of 1.0 mSv−y.

Role of zinc oxide nanoparticles in alleviating hepatic fibrosis and nephrotoxicity induced by thioacetamide in rats

The present research studied the influence of zinc oxide nanoparticles (ZnO-NPs; 5, 7.5, and 10 mg/kg, i.p.) on the liver and kidney injuries motivated by thioacetamide (TAA; 100 mg/kg, i.p.). Each treatment was carried out 3 times per week for 8 weeks. ZnO-NPs relieved the decrease of hepatic or renal reduced glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD) induced by TAA. Moreover, ZnO-NPs lowered tissue malondialdehyde (MDA, an indicator for lipid peroxidation). TAA treatment led to a significant increase in plasma inflammatory markers (TNF-α, IL-6), liver enzymes (gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and kidney function parameters (creatinine, urea, uric acid). However, these parameters were reduced after treatment with ZnO-NPs. In addition, the hepatic fibrosis markers, hydroxyproline level, and α-smooth muscle actin immunopositive stain were lowered by ZnO-NPs. The protective effect of ZnO-NPs in respect to biochemical changes was also confirmed by histopathological and immunohistochemistry studies in the liver and kidney sections. Our results suggested that ZnO-NPs may attenuate TAA toxicity via suppression of oxidative stress.

PIXE study on the effects of parathyroid hormone on elemental content in rat bones

Parathyroid hormone (PTH) has attracted considerable interest as a bone anabolic agent. PTH plays a central role in regulating calcium phosphate metabolism and its increases in production in response to low serum calcium levels. A continuous hypersecretion of PTH, as occurs in primary hyperparathyroidism, leads to bone resorption. In this study, the effect of different doses of parathyroid hormone (PTH) on bone mineral content (BMC) in rats was investigated by particle-induced X-ray emission (PIXE). This study will help in investigating further the toxicity of extremely high doses of PTH on BMC. For this study, PTH at doses of 15, 45, or 135μg/kg/day were applied to 9-month-old male and female Sprague Dawley (SD) rats. The concentrations of calcium (Ca), phosphorus (P), strontium (Sr), and zinc (Zn) were measured for bone treatment of PTH. From the results of the research, it was revealed that the biomechanical characteristics of the bone as well as the bone mass were enhanced after the treatment. It was further found that the concentrations of other elements also increased, excluding Zn. This research proved that PTH assists in the treatment of osteoporosis as revealed by the characteristics of different elements. PIXE can be used to determine the concentrations of bone mineral content.

RETROSPECTIVE ANALYSIS OF PATIENT RADIATION DOSES IN DIGITAL CORONARY ANGIOGRAPHY AND INTERVENTIONS

This study sought to assess patient and operator eye lens doses in diagnostic coronary angiography (DCA) and percutaneous coronary interventions (PCI) in a University hospital in Oman. Kerma area product (PkA), cumulative air kerma (CAK) and fluoroscopic time (FT) were retrospectively recorded from the DICOM header for 264 patients. The median (interquartile range) of FT, PKA and CAK were: 5.3 min (2.6-10.5), 60.9 Gy cm2 (41.3-91.4) and 0.86 Gy (0.61-1.29), respectively, for DCA procedures, and they were 20.2 min (13.3-30.1), 174.0 Gy cm2 (113.7-253.3) and 2.6 Gy (1.8-3.9), respectively, for PCI procedures. The results revealed wide variability in patient doses among individual patients. Monitoring and recording patient dose data can be valuable for quality assurance and patient safety purposes. Feedback to the operator may help optimize radiation doses to patients and prompt further action, as needed.

Synthesis and Characterization of an Efficient New Liquid Laser Dye Material - Chalcone (DMAPPP)

Synthesis and Characterization of an Efficient New Liquid Laser Dye Material — Chalcone (DMAPPP) A.O. Elzupirc,d,∗, K.H. Ibnaouf, H. Idriss, M.A. Ibrahem, S. Prasad , M.A. Alrajhi, M.S. AlSalhi and A.S. Alaamer Al Imam Mohammad Ibn Saud Islamic University (IMSIU), College of Science, Physics Department, P.O. Box 90950, Riyadh, 11623, Saudi Arabia Alneelain University, School of Physics, Faculty of Science and Technology, P.O. Box 12702, Khartoum, 11121 Sudan Al Imam Mohammad Ibn Saud Islamic University (IMSIU), College of Science, Committee on Radiation and Environmental Pollution Protection, Riyadh, KSA Ministry of Higher Education, Central Laboratory, Khartoum, Sudan Ministries of Higher Education and Scientific Research, Sudan Atomic Energy Commission, Khartoum, Sudan KSU Research Chair on Laser Diagnosis of Cancers, College of Science, King Saud University, Riyadh, 11451 Saudi Arabia Department of Physics and Astronomy, College of Science, Riyadh, 11451 Saudi Arabia