Abdullah Kayar

Total oxidant and antioxidant capacities, nitric oxide and malondialdehyde levels in cats seropositive for the feline coronavirus.

Feline coronavirus (FCoV) is a highly contagious virus that is ubiquitous in multicat environments and may induce oxidative stress. This virus commonly causes an asymptomatic infection, which can persist in certain individuals. Sporadically and unpredictably, FCoV infection leads to feline infectious peritonitis (FIP), a highly fatal systemic immune-mediated disease. There are no data in the veterinary literature relating to oxida - tive stress in FCoV. Antioxidant capacity (TAC) can be attributed to single components in the defence systems against free radicals. The measurement of the total oxidant status (TOS) accurately reflects the oxidative status of blood plasma or serum. Nitric oxide (NO) acts as a free radical and contributes to host defences against oxida - tion. Malondialdehyde (MDA) is a reliable and commonly used marker of overall lipid peroxidation levels and the presence of oxidative stress. This study aimed to determine levels of oxidative stress markers, serum TAC, total oxidant capacity (TOC), NO and serum MDA in 24 cats seropositive for FCoVs and 15 cats seronegative for FCoVs. Significantly higher serum TOC, NO and MDA levels were found in seropositive animals ( P < 0.001, P < 0.05 and P < 0.001, respectively) than in seronegative animals. In contrast, serum TAC levels were found to be significantly lower in seropositive cats compared with seronegative cats ( P < 0.001). The results of the present study suggest that FCoV seropositivity is associated with oxidative stress and decreased antioxidant status.

Bacterial species isolated from cats with lower urinary tract infection and their susceptibilities to cefovecin

BackgroundThe aim of this study was to determine the bacterial species recovered from 61 cats with lower urinary tract infection (LUTI), and their susceptibility to cefovecin in vitro.ResultsThe clinical signs and final clinical diagnosis for cats with confirmed LUTI were also reported. After physical examination of the cats, urine samples including ≥5-6 leucocytes in microscopic evaluation were cultured using bacteriological techniques. The isolates were identified by conventional microbiological methods and tested for in vitro susceptibility using the Kirby-Bauer disc diffusion method recommended by the Clinical Laboratory Standards Institute. Bacterial growth was observed in 16 of 61 urine samples. Antimicrobial susceptibility tests showed that 13 of 16 (81%) isolates were susceptible to cefovecin. The most frequently isolated bacterium from cats with signs of lower urinary tract infection, was Escherichia coli.ConclusionCefovecin was found to be effective in cats with LUTI. Because cefovecin is a new antimicrobial agent in veterinary medicine, there are only few studies about urine culture of cats with LUTI. It is the first study on in vitro activity of cefovecin against bacterial isolates from cats with lower urinary infections in Istanbul, Turkey.

Prevalence of systemic disorders in cats with oral lesions

Oral disorders of small animals constitute a problem for veterinarians. Chronic oral infections are commonly seen in domestic cats. The objectives of this study were to characterise feline oral lesions, common feline dental problems, and especially the association of oral disease and systemic disease in cats. Two hundred and twenty cats referred over a period of 33 months to the Internal Medicine Department of our University with signs of oral disorders were included in this prospective study and were examined for the occurrence of the most commonly seen diseases. Infectious diseases which frequently cause ulcers and/or erosions within the mouth and on the tongue, constituted a significant proportion of the cases identified in this study. Feline Coronavirus (FCoV) infection was diagnosed in 36 cats (16%), Feline Calicivirus (FCV) in 17 cats (8%) and 16 cats (7%) had three viral infections (FCoV + Feline Immunodeficiency Virus (FIV) + Feline Leukemia Virus (FeLV)) at the same time. We conclude that oral disorders may be a sign of underlying systemic diseases in cats, especially in those diagnosed with feline viral infections. Other diagnosed diseases included immune-mediated disorders, eosinophilic granuloma complex, gastrointestinal system disorders, nutritional disorders, diabetes mellitus, hepatic disorders and chronic renal failure. Therefore, the first step in preventing oral disease in animals must be routine physical examination which includes a comprehensive oral exam.

PAREZİSLİ BİR KÖPEKTE SAPTANAN LENFOMA OLGUSU

OZET Norolojik sikayetlerle klinigimize getirilen 2 yasli Boxer irki erkek bir kopekte multisistemik bir hastaligin bulundugu dusunulerek, klinik ve laboratuvar muayeneleri yapildi. Lenfadenopati saptanan hastada igne aspirasyon biyopsisi ile yapilan sitolojik kontroller sonucunda, kopeklerde gorulen en yaygin neoplazmalardan birisi olan lenfoma teshisi dogrulandi. Neoplastik lezyon suphesi bulunan kucuk hayvanlarda igne aspirasyonu ile toplanan sitolojik orneklerin muayenesi sonucunda kesin teshise kolayca gidilebilecegi kanisina varildi. Anahtar Kelimeler: Kopek, lenfoma, igne-aspirasyon biyopsisi. A CASE REPORT: LYMPHOMA IN A DOG WITH PARESIS ABSTRACT Clinic and laboratory examinations were performed on a 2 year old, male, Boxer dog. The dog is believed to have a multi-systemic disease. Cytological examinations that conducted in the samples obtained by fine-needle aspiration biopsy from the dog with lymhadenopathy confirmed the diagnosis of lymphoma, which is one of commonly diagnosed neoplasms in dogs. It is concluded that definitive diagnosis of suspected neoplastic lesions in small animals can be easily made based on the results of cytological exminations of samples obtained by fine-needle aspiration. Key words: Dog, lymphoma, fine-needle aspiration.